Prophylaxis and Treatment for Leptospirosis: Where are the Evidences?

Leptospirosis is one on those many diseases which expresses itself in the form of outbreaks associated with seasonal variations like rainfall. Pathogenic organism responsible for this disease is a spirochete of genus Leptospira which exists in around 300 serovars.[3] Leptospirosis presents itself in a wide spectrum of clinical presentations frequently mimicking other diseases, so frequently it is misdiagnosed or under diagnosed. Spectrum of disease may range from mild infection to life threatening pulmonary and renal complications and case fatality may goes up to 20%.